A review: Current trends and future perspectives of bacterial nanocellulose-based wound dressings

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Khatarina Meldawati Pasaribu, I. Putu Mahendra, Myrtha Karina, Nanang Masruchin, Novia Amalia Sholeha, Saharman Gea, Abhishek Gupta, Brian Johnston, Izabela Radecka

2024 International Journal of Biological Macromolecules Vol. 279 Review Cited by 18 SDG 17SDG 3 Quartile

Abstract

Bacterial cellulose (BC) has gained significant attention as a base material for wound dressings due to its superior physical properties, biocompatibility, and non-toxicity. However, to produce wound dressings that actively facilitate wound healing, BC modification is essential. To provide a comprehensive analysis of the potential research developments and the trends in bacterial cellulose-based wound dressings (BCWD), this review focuses on the BCWD research conducted in the last decade. The review highlights the optimization of BC usage as a base material for active wound dressing, including the incorporation of miscellaneous materials and the enhancement of BC properties such as ultra-transparency, anti-leakage, stretchability/flexibility, adhesiveness, conductivity, injectability, pattern, and pH-sensor ability. © 2024 Elsevier B.V.

Affiliations

Research Center for Biomass and Bioproducts, National Research and Innovation Agency of Indonesia (BRIN), Cibinong, 16911, Indonesia; Research Collaboration Center for Biomass and Biorefinery, Padjajaran Science and Technopark, Jl. Ir. Soekarno, Km.21, Jatinangor, 45363, Indonesia; Research Collaboration Center for Nanocellulose, BRIN - UNAND, Padang, 25163, Indonesia; Cellulosic and Functional Materials Research Centre, Universitas Sumatera Utara, Jl. Bioteknologi No.1, Medan, 20155, Indonesia; Program Studi Kimia, Jurusan Sains, Institut Teknologi Sumatera, Jalan Terusan Ryacudu, Way Hui, Jati Agung, Lampung Selatan, 35365, Indonesia; College of Vocational Studies, Bogor Agricultural University (IPB University), Jalan Kumbang No. 14, Bogor, 16151, Indonesia; Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Sumatera Utara, Jl. Bioteknologi No. 1, Medan, 20155, Indonesia; Research Institute in Healthcare Science, Faculty of Science and Engineering, University of Wolverhampton, Wulfruna Street, Wolverhampton, WV1 1LY, United Kingdom; School of Pharmacy, Faculty of Science and Engineering, University of Wolverhampton, Wulfruna Street, Wolverhampton, WV1 1LY, United Kingdom; Wolverhampton School of Sciences, Faculty of Science and Engineering, University of Wolverhampton, Wulfruna Street, Wolverhampton, WV1 1LY, United Kingdom

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