Najah Fadilah Putri, Rita Arbianti, Ibnu Maulana Hidayatullah, Yuswan Muharam, Tania Surya Utami, Fauzi Yusupandi, Ramaraj Boopathy
Amoxicillin (AMX), a commonly used antibiotic, has been found in surface waters globally. It has raised environmental concerns due to potential risks such as generating antibiotic resistance, genotoxicity, and disruption of ecology. This study investigates the prospect for Amoxicillin degradation using a Microbial Fuel Cell (MFC) powered by a native microbial community. This research encompasses an analysis of the degradation profile, electricity generation, and microbes involved in the process. Prior to acclimatization (using 1000 Ω external resistance), experiments were conducted for a duration of 72 h, during which the initial concentration and pH value of amoxicillin were altered. Electric potential was measured, and amoxicillin content was determined using High Performance Liquid Chromatography (HPLC). Microbial community composition was evaluated through 16S rRNA sequencing. Amoxicillin reduction were 17.85 ± 4.35 %, 42.82 ± 2.78 %, and 66.17 ± 0.47 %, with corresponding power generation values of 450.99, 267.55, and 171.99 μW/m2 for starting amoxicillin concentrations of 10, 20, and 30 mg/L, respectively. The experiment produced a maximum power of 972.97 μW/m2 at pH 8.2 with a 73.42 ± 6.93 % reduction in AMX. A microbial community composition shift was detected and an exoelectrogen, Chromobacterium, was identified as the dominating microbe post-operation. This study underscores the potential of MFCs in amoxicillin degradation, providing valuable insights for future advancements of antibiotics and pharmaceuticals removal in wastewater remediation. © 2024 Elsevier Ltd
Department of Chemical Engineering, Faculty of Engineering, Universitas Indonesia, West Java, Depok, 16424, Indonesia; Bioprocess Engineering Study Program, Faculty of Engineering, Universitas Indonesia, West Java, Depok, 16424, Indonesia; Research Center for Biomass Valorization, Universitas Indonesia, West Java, Depok, 16424, Indonesia; Department of Chemical Engineering, Institut Teknologi Sumatera, Lampung Selatan, Lampung, 35365, Indonesia; Department of Biological Sciences, Nicholls State University, Thibodaux, 70310, LA, United States