Riesca Ayu Kusuma Wardhani, Aditta Putri Aulia Haqque, Lia A.T.W. Asri, Heni Rachmawati, Khairurrijal, Bambang Sunendar Purwasasmita, Luqman Buchori
An ideal wound dressing must be biocompatible, not cause allergies, and can protect the wounds from microorganisms and foreign particles. In this work, we employed the electrospinning method to fabricate a novel nanofiber membrane wound dressing from a mixture of chitosan, polyethylene oxide (PEO), and botanical collagen extracted from taro tuber (Colocasia esculenta). Scanning electron microscope (SEM) images of the resulting chitosan-PEO-botanical collagen nanofiber membrane showed braided fibers with a diameter from 50 to 292 nm. Attenuated total reflectance Fourier Transform Infrared (ATR-FTIR) spectroscopy showed that the nanofiber membrane forms hydrogen bond interactions. In the culture-based assay, the nanofiber membrane demonstrated antibacterial activity against Gram-positive Staphylococcus aureus and Gram-negative Pseudomonas aeruginosa bacteria. The results showed that the chitosan-PEO-botanical collagen nanofiber membrane has excellent potential for use as antibacterial wound dressing material. © 2026 American Institute of Physics Inc.. All rights reserved.
Research Center for Nanotechnology Systems, National Research and Innovation Agency (BRIN), South Tangerang, Banten, 15314, Indonesia; Directorate of Laboratory Management, Research Facilities, and Science and Technology Park, National Research and Innovation Agency (BRIN), South Tangerang, Banten, 15314, Indonesia; Materials Science and Engineering Research Group, Faculty of Mechanical and Aerospace Engineering, Institut Teknologi Bandung, Bandung, 40132, Indonesia; School of Pharmacy, Institut Teknologi Bandung, Bandung, 40132, Indonesia; Research Center for Nanosciences and Nanotechnology, Institut Teknologi Bandung, Bandung, 40132, Indonesia; Physics and Technology of Advanced Materials, Department of Physics, Faculty of Mathematics and Natural Sciences, Institut Teknologi Bandung, Bandung, 40132, Indonesia; Department of Physics, Faculty of Science, Institut Teknologi Sumatera, Lampung, 35365, Indonesia; Advanced Materials Processing Group, Engineering Physics Study Program, Institut Teknologi Bandung, Bandung, 40132, Indonesia; Chemical Engineering Department, Dipenogoro University, Kampus Undip Tembalang,, Central Java, Semarang, 50275, Indonesia
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